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Thinking about taking a fluconazole pill for yeast infections? Or, perhaps you already are taking one, or a similar azole pill. If you have spent time on Candida Hub, you will likely know there are a wide variety of natural alternatives that can be just as powerful; and even more powerful than prescription antifungals. Additionally, natural remedies can augment any synthetic drug you may be taking at the moment. Consequently, nature’s medicinal plants are a great alternative and addition to a treatment regimen; not to mention they are much safer to utilize.
So let’s talk first, about perhaps, the most important issue regarding fluconazole pills: the side effects. This information is especially important to understand if you are pregnant or think you will become pregnant.
Fluconazole Pill Side Effects
One study you may not have heard about found that fluconazole can very rarely be lethal to babies in their mother’s wombs. Even if the child does survive a fluconazole regimen, it can be scarred for life due to the physical anomalies, that this drug can cause. This should not be surprising as fluconazole has a history of causing teratism (an anomaly of organic form and structure) in animals.
The three women documented in this study received fluconazole through or beyond the first trimester of pregnancy. The women in the study could not be seen to be taking, or exposed to, any other substance which could cause such pregnancy complications. The researches concluded, that fluconazole was able to cause birth defects in children. They suggested all women, who might become pregnant, should be informed before taking this drug. Additionally, the researchers also speculated that all other azole drugs (miconazole is one of these, and the primary ingredient in Monistat) had the potential to cause birth defects as well. The study concludes by stating:
We conclude that fluconazole is teratogenic in humans and that related azoles are likely to be teratogenic in humans as well. Each woman of [childbearing] age given fluconazole or a related azole should be counseled about the possibility of birth defects and should be offered effective birth control methods.
http://dx.doi.org/10.1093/clinids/22.2.336
This study of the three women and fluconazole was published in Clinical Infectious Diseases [(1996) 22 (2):336-340]. The recommended human dose will likely not cause birth defects, it is 4mg / kg of body weight. This research states the effect of oral fluconazole has been investigated in rats. In many of these studies, maternal weight gain was impaired and placental weights were elevated. At doses of 25mg / kg and 50mg / kg of body weight and higher, delays in fetal ossification (the natural process of bone formation), fetal anatomical distortion such as supernumerary (present in excess of the normal number) ribs, and dilation of the renal pelvis were noted; however, doses of 5mg / kg and 10mg / kg of body weight, for the rats, did not cause these anomalies.
Another study does support the causal relationship between fluconazole and birth defects. The researchers do state that at very low dose, less than 150mg, this antifungal does appear to be safe during pregnancy. Higher doses are not recommended during pregnancy. According to the study:
There is evidence to suggest that fluconazole exhibits dose-dependent teratogenic [Any agent that can disturb the development of an embryo or fetus] effects; however, it appears to be safe at lower doses (150 mg/day). Ketoconazole, flucytosine, and griseofulvin have been shown to be teratogenic and/or embryotoxic in animals. Iodides have been associated with congenital goiter and should not be used during pregnancy.
http://dx.doi.org/10.1086/514977
Almost every study I looked at regarding fluconazole, showed that there was, in fact, a slightly increased rate of birth defects. For some reason many studies said it was not too statistically significant; however the Use of Oral Fluconazole during Pregnancy and the Risk of Birth Defects study, published in the The New England Journal of Medicine [2013;369:830-9], found that the risk of tetralogy of Fallot was certainly significantly increased due to fluconazole: over 3 times increased. The study states:
A significantly increased risk of tetralogy of Fallot was observed (7 cases in fluconazole-exposed pregnancies [prevalence, 0.10%] as compared with 287 cases in unexposed pregnancies [prevalence, 0.03%]; adjusted prevalence odds ratio, 3.16; 95% CI, 1.49 to 6.71).
http://dx.doi.org/10.1056/NEJMoa1301066
There is little that can justify any increased risk to a child simply to get rid of a yeast infection with a prescription drug. There are safer alternatives out there. And, although many studies will seemingly overlook slight increases in birth abnormalities, even small increases are important to consider given a yeast infection is rarely life threatening. I think the researchers from the 1998 Clinical Infectious Diseases study were correct when they said “Careful consideration of the benefit to the mother and the risk to the fetus is required when prescribing antifungal therapy in pregnancy.”
A 1/2 Day & Yeast is Gone!
Linda Allen suffered from yeast infections for years. Through researching natural medicine & Candida, she found an efficacious solution!
Linda is one expert you want on your side! Let her show you how to get rid of a superficial yeast infection in just 12 hours; AND, keep it gone!
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Visit Official Site!Fluconazole and Children
Children were shown to develop a significant rate of adverse side effects when taking fluconazole. Mostly, these side effects were gastrointestinal related; i.e., diarrhea and vomiting. Of 382 children taking fluconazole, 45 developed side effects (about 12%). 7 of the children developed skin conditions due to this drug. 4 children developed either cardiovascular or central and peripheral nervous side effects. Other side effects were reported by the study as well. The children were administered in the range of 1 to 12 mg of fluconazole per kilogram of body weight. As a result, over 1 in 10 children who take fluconazole will probably develop some health malady as a result. This study was published in Antimicrobial Agents and Chemotherapy [Aug. 1999, p. 1955–1960].
Eliminate Bacterial Vaginosis & Vaginal Odor
Jennifer O’Brien is one prominent expert on BV that knows how to get rid of vaginal odor. BV is a common infection that you don’t have to put up with.
Jennifer will show you how to naturally eliminate vaginal odor in just 3 days.
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Visit Official Site!Common Fluconazole Pill Medication Side Effects
There are a wide variety of unwanted health problems, that can result at times, for individuals who take fluconazole. Here are some of the severe, and mild, side effects that you could experience when you take this drug. Some of these side effects may be dose dependant; and, could be more severe if higher doses are taken into the body.
Severe Side Effects
- Infant mortality (if taken during pregnancy)
- Birth defects (if taken during pregnancy)
- Extreme fatigue
- Seizures
- Trouble breathing or swallowing
- Unusual Blistering or peeling skin
Less Severe Side Effects
- Reduced or non-existent appetite
- Stomach pains
- Yellow discoloration of the eyes and skin
- Flu-like symptoms
- Unusually dark urine and pale stools
- Hives
- Unusual itching
- Swelling of various body parts (typically found in the hands, feet, ankles, lower legs, face, throat, lips, tongue, or eyes)
- Headache
- Vertigo
- Inability to taste food
- Heartburn
Clair Goodall: Author & Nature Lover
Clair Goodall is a bee-obsessed natural medicine convert from Minnesota. She is one expert you might want to know more about!
Clair will help you protect you and your family from toxic products and chemicals and help you discover solutions from nature.
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Visit Official Site!Naturally Treating Yeast Infections Safely
According to a research paper published in Clinical Microbiology Reviews [12.1 (1999): 80-96], Candida species are quite ubiquitous organisms. Candida are most frequently present in the mouth; and, live in 31% to 55% of healthy people. The species that causes approximately 70% to 80% of all Candida infections is C. albicans.
The Chinese Journal of Obstetrics and Gynecology [2011 Jul;46(7):496] reports there appears to be a correlation between intestinal Candida infections and vaginal yeast infections. And, this provides a clue, as to why yeast infections in general, can reoccur.
This study states, in 148 cases of vaginal candida infections, 33.1% of the women were infected in both the intestines and vaginal area. The recurrence rate of yeast infections, in women with simultaneous intestinal infection, was significantly higher than for women who did not have an intestinal infection. This study concluded that vaginal yeast infections are highly associated with simultaneous intestinal Candida infection.
As research appears to indicate, systemic Candida infections can and do happen. A more systemic Candida infection may primarily get a foothold in the intestines; and cause a wide array of problems. If your yeast infections keep happening, a systemic Candida problem may be why.
One woman who suffered from a systemic Candida infection, for about 12 years, was Linda Allen. The systemic Candida infection that attacked Linda caused a wide range of health problems in addition to yeast infections. Some of these problems, Linda describes in her own words in the following quote:
To be honest, it was hard to pinpoint exactly what was wrong: I wasn’t really sick, but I wasn’t really well either. I had listlessness, fatigue, brain fog, stomach ailments, unexplained rashes, skin infections, and so on. It seemed like every day brought a new challenge.
My energy was sapped and I felt exhausted, which affected my grades and put a big dent in my social life.
Linda Allen’s symptoms included an embarrassing vaginal discharge, severe itching, and burning sensations. Her infections were difficult to deal with, and Linda’s health problems cost her financially as well. Linda states these infections of Candida can become excruciating when they happen as frequently as a menstrual period.
Yet, Linda spent a great deal of time in research; and even questioned health professionals who were kind enough to share some time with her. Linda even tried an array of purported "cures." Although it took a while, eventually, Linda put together a natural treatment plan she hoped would solve her Candida situation.
After spending about a year refining her new approach, Linda tried her system on herself. It worked amazingly well. Linda even returned to a few medical doctors to get tested for the presence of infections. These tests revealed all indicators of infection had vanished! Linda was indeed well again, after such a long, difficult journey.
Linda has since published a book detailing how to copy her success. She also includes a 12 hour yeast infection cure that can get rid of a superficial (such as a genital yeast infection or oral thrush) yeast infection in about 12 hours.
Linda’s publisher protects those who get her book with a 60 day, 100% money back guarantee. Linda’s publisher, a subsidiary of the United States based firm Keynetics Incorporated, is a reputable digital retailer that has been around for a long time. They have great customer service, and make getting a full refund on Linda’s book quick and easy. If you’re not satisfied, you can quickly get all your money back.
If you would like to learn more about Linda’s journey to freedom from Candida, see reviews of others who tried her natural system, or find out more about her efficacious book; you can find more information at Linda Allen’s website.
Further Study
Candida Hub has a wide variety of articles on common natural remedies used to treat yeast overgrowth. They can benefit both men and women. If you have the time, you can explore the other areas of this site and start building your knowledge about Candida and natural medicine. One article that may interest you talks specifically about fluconazole: Candida glabrata and fluconazole.
Author: Mr. Nicholas Gross
Nick Gross is a natural medicine enthusiast who has been researching and writing about natural medicine since 2008. Nick is primarily a web developer but also researches and authors written and video content about natural health. Nick has a bachelor’s degree in Management Information Systems from the University of Northern Iowa.
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SOURCES:
- http://dx.doi.org/10.1093/clinids/22.2.336 — Fluconazole-Induced Congenital Anomalies in Three Infants. Clinical Infectious Diseases [(1996) 22 (2):336-340]
- http://dx.doi.org/10.1086/514977 — Antifungal Therapy During Pregnancy. Clinical Infectious Diseases [(1998) 27 (5):1151-1160]
- http://dx.doi.org/10.1056/NEJMoa1301066 — Use of Oral Fluconazole during Pregnancy and the Risk of Birth Defects. The New England Journal of Medicine [2013;369:830-9]
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC89397/ — Safety and Tolerability of Fluconazole in Children. Antimicrobial Agents and Chemotherapy (Aug. 1999, p. 1955–1960)
- https://www.nlm.nih.gov/medlineplus/druginfo/meds/a690002.html — Medline Plus: Fluconazole. Side effects of fluconazole.
- https://doi.org/10.1128/CMR.12.1.80 -- Fidel, Paul L., Jose A. Vazquez, and Jack D. Sobel. "Candida glabrata: review of epidemiology, pathogenesis, and clinical disease with comparison to C. albicans." Clinical Microbiology Reviews [12.1 (1999): 80-96].
- https://pubmed.ncbi.nlm.nih.gov/22041440/ -- Lin XL, Li Z, Zuo XL. "Study on the relationship between vaginal and intestinal candida in patients with vulvovaginal candidiasis." Chinese Journal of Obstetrics and Gynecology (Zhonghua fu chan ke za zhi). [2011 Jul;46(7):496].
