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Candida Hyphae Germ Tubes

Candida albicans Hyphal Germ Tube Growth

 

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Pictured here is the yeast Candida albicans. The red arrow in the picture points to a hyphal (germ tube) growth. The blue arrows indicate single cells of the yeast that have not grown into hyphal structures.
Pictured here is the yeast Candida albicans. The red arrow in the picture points to a hyphal (germ tube) growth. The blue arrows indicate single cells of the yeast that have not grown into hyphal structures.

Candida albicans is a dimorphic type of yeast; this means it exists in two different forms. The less pathogenic form does not have tendrils; and, merely exists as a cell—this is called its blastoconidia form. However, Candida albicans can become more aggressive; and, develop long tendrils (or germ tubes) known as hyphae. These tendrils can burrow into your skin. This allows the fungus to gain a greater foothold in your body; and, acquire more nutrients to grow.

A study published in the journal Virulence [2013 Feb 15; 4(2): 119–128] showed that Candida albicans has a tendency to grow hyphal germ tubes when the pH of its environment is high; about a 7 on the pH scale. Lower pH levels, are also able to keep Candida albicans in its blastoconidia budding yeast form, which is less pathogenic. Candida of all kinds prefer a more alkaline environment; and, keeping an envrionment’s pH low, will also discourage its overall growth. For women with a yeast infection, it is wise to use a pH balancing tampon or a menstrual pad, instead of a regular tampon. Having a tampon in place will allow blood (which has a higher pH) to dilute the vagina, and raise the natural pH of the vagina to undesirable levels. The study, which addressed tampon usage in the presence of yeast overgrowth, was published in the International Journal of Gynecology and Obstetrics [85.3 (2004): 298-300].

Aside from growing of hyphal germ tubes, Candida species also pose greater threat to you via becoming drug resistant and their formation of biofilm. As we will discuss, these two things are probably the reason over the counter, or prescription azole drugs (such as fluconazole), are not getting rid of your yeast infection—for those of you who are not seeing immediate results, that is.

A 1/2 Day & Yeast is Gone!

Linda Allen suffered from yeast infections for years. Through researching natural medicine & Candida, she found an efficacious solution!

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Candida with Biofilm: 1000 Times More Resistant

One study, that reported some interesting findings, was published in the Journal of Antimicrobial Chemotherapy [(2012) 67 (3): 618-621]. The study found that Candida, when it has formed a biofilm, was about 1024 times more resistant to conventional antifungal drugs. This may explain why, if you haven’t seen results from conventional azole antifungal drugs, your yeast infection isn’t being cured after drug therapies.

Biofilm is a layer of sludge that yeast cells sometimes form to protect themselves. Biofilm formation is a common feature of certain microbiological organisms. This film effectively inhibits Candicidal materials from even coming in contact with the actual fungus; giving it over a thousand times more resistance to drugs.

Fortunately, natural remedies such as herbs and essential oils can drastically reduce the ability of biofilm to protect Candida. The study in the Journal of Antimicrobial Chemotherapy [(2012) 67 (3): 618-621] found that cinnamon essential oil was capable of killing Candida that had pre-formed biofilms. And, the natural cinnamon oil, was also able to increase the effectiveness of antifungal drugs; making it a great addition to any prescription drug you may be taking. Other essential oils and herbs, can probably be of great use for combating Candida, as they could help break up protective biofilm. If you’d like to read a bit more about how cinnamon can treat stubborn yeast infections, consider perusing this article: Cinnamon Essential oil for Yeast Infection.

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Jennifer O’Brien is one prominent expert on BV that knows how to get rid of vaginal odor. BV is a common infection that you don’t have to put up with.

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Drug Resistance and Candida Infections

Candida that has developed germ tubes and biofilm can be drastically more resistant to antifungal drugs.  Pictured here are products containing the azole antifungal drug fluconazole.
Candida that has developed germ tubes and biofilm can be drastically more resistant to antifungal drugs. Pictured here are products containing the azole antifungal drug fluconazole.

Candida does have the ability to rapidly acquire drug resistance. This means, that changes occur in cellular metabolism, which make typically effective substances of no use in killing Candida. A study conducted on the second leading species of Candida to infect people, Candida glabrata, examined how rapidly this fungus would develop resistance to fluconazole. The study was published in the journal Antimicrobial Agents and Chemotherapy [February 2005 vol. 49 no. 2 pp. 783-787]. The study found that Candida glabrata developed significant fluconazole resistance within just 4 days of being exposed to this drug.

If you have had repeat yeast infections, and have been using antifungal drugs, the yeast could have become resistant to these medications. If you are simply not seeing results with synthetic chemicals, you should investigate natural remedies that are proven to kill even drug resistant strains of Candida.

Clair Goodall: Author & Nature Lover

Clair Goodall is a bee-obsessed natural medicine convert from Minnesota. She is one expert you might want to know more about!

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A Natural, 12 Hour Yeast Infection Cure

Linda Allen’s Yeast Infection No More

According to a research paper published in Clinical Microbiology Reviews [12.1 (1999): 80-96], Candida species are quite ubiquitous organisms. Candida are most frequently present in the mouth; and, live in 31% to 55% of healthy people. The species that causes approximately 70% to 80% of all Candida infections is C. albicans.

The Chinese Journal of Obstetrics and Gynecology [2011 Jul;46(7):496] reports there appears to be a correlation between intestinal Candida infections and vaginal yeast infections. And, this provides a clue, as to why yeast infections in general, can reoccur.

This study states, in 148 cases of vaginal candida infections, 33.1% of the women were infected in both the intestines and vaginal area. The recurrence rate of yeast infections, in women with simultaneous intestinal infection, was significantly higher than for women who did not have an intestinal infection. This study concluded that vaginal yeast infections are highly associated with simultaneous intestinal Candida infection.

As research appears to indicate, systemic Candida infections can and do happen. A more systemic Candida infection may primarily get a foothold in the intestines; and cause a wide array of problems. If your yeast infections keep happening, a systemic Candida problem may be why.

One woman who suffered from a systemic Candida infection, for about 12 years, was Linda Allen. The systemic Candida infection that attacked Linda caused a wide range of health problems in addition to yeast infections. Some of these problems, Linda describes in her own words in the following quote:

To be honest, it was hard to pinpoint exactly what was wrong: I wasn’t really sick, but I wasn’t really well either. I had listlessness, fatigue, brain fog, stomach ailments, unexplained rashes, skin infections, and so on. It seemed like every day brought a new challenge.

My energy was sapped and I felt exhausted, which affected my grades and put a big dent in my social life.

Linda Allen’s symptoms included an embarrassing vaginal discharge, severe itching, and burning sensations. Her infections were difficult to deal with, and Linda’s health problems cost her financially as well. Linda states these infections of Candida can become excruciating when they happen as frequently as a menstrual period.

Yet, Linda spent a great deal of time in research; and even questioned health professionals who were kind enough to share some time with her. Linda even tried an array of purported "cures." Although it took a while, eventually, Linda put together a natural treatment plan she hoped would solve her Candida situation.

After spending about a year refining her new approach, Linda tried her system on herself. It worked amazingly well. Linda even returned to a few medical doctors to get tested for the presence of infections. These tests revealed all indicators of infection had vanished! Linda was indeed well again, after such a long, difficult journey.

Linda has since published a book detailing how to copy her success. She also includes a 12 hour yeast infection cure that can get rid of a superficial (such as a genital yeast infection or oral thrush) yeast infection in about 12 hours.

Linda’s publisher protects those who get her book with a 60 day, 100% money back guarantee. Linda’s publisher, a subsidiary of the United States based firm Keynetics Incorporated, is a reputable digital retailer that has been around for a long time. They have great customer service, and make getting a full refund on Linda’s book quick and easy. If you’re not satisfied, you can quickly get all your money back.

If you would like to learn more about Linda’s journey to freedom from Candida, see reviews of others who tried her natural system, or find out more about her efficacious book; you can find more information at Linda Allen’s website.

Author: Mr. Nicholas Gross

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Nick Gross is a natural medicine enthusiast who has been researching and writing about natural medicine since 2008. Nick is primarily a web developer but also researches and authors written and video content about natural health. Nick has a bachelor’s degree in Management Information Systems from the University of Northern Iowa.

+ About Nick Gross

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SOURCES:

  • http://dx.doi.org/10.1016/j.ijgo.2004.03.003 — Efficacy of a novel pH-buffering tampon in preserving the acidic vaginal pH during menstruation. International Journal of Gynecology & Obstetrics [85.3 (2004): 298-300]. PDF Available Here
  • http://dx.doi.org/10.4161/viru.22913 — Mayer FL, Wilson D, Hube B. Candida albicans pathogenicity mechanisms. Virulence [2013; 4(2):119-128] Full Text Available Here
  • http://dx.doi.org/10.1093/jac/dkr512 — Antibiofilm activity of certain phytocompounds and their synergy with fluconazole against Candida albicans biofilms. Journal of Antimicrobial Chemotherapy [(2012) 67 (3): 618-621]
  • https://dx.doi.org/10.1128/AAC.49.2.783-787.2005 — Rapid Acquisition of Stable Azole Resistance by Candida glabrata Isolates Obtained before the Clinical Introduction of Fluconazole. Antimicrobial Agents and Chemotherapy [February 2005 vol. 49 no. 2 p. 783-787]
  • https://doi.org/10.1128/CMR.12.1.80 -- Fidel, Paul L., Jose A. Vazquez, and Jack D. Sobel. "Candida glabrata: review of epidemiology, pathogenesis, and clinical disease with comparison to C. albicans." Clinical Microbiology Reviews [12.1 (1999): 80-96].
  • https://pubmed.ncbi.nlm.nih.gov/22041440/ -- Lin XL, Li Z, Zuo XL. "Study on the relationship between vaginal and intestinal candida in patients with vulvovaginal candidiasis." Chinese Journal of Obstetrics and Gynecology (Zhonghua fu chan ke za zhi). [2011 Jul;46(7):496].